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Spinothalamic Tract - AnatomyZone This diagram illustrates the spinothalamic tract (also known as the anterolateral system/ventrolateral system). The spinothalamic tract is one of the ascending sensory tracts which conveys sensory information from the periphery to the central processing systems. There are three main ascending (afferent) pathways which convey sensory information: Pain Transmission Pathway - Opioid Peptides Diagram illustrating the route of the ascending transmission pathway. Ascending pain pathway: All opioids, regardless of the initial receptor they bind to, utilize a similar pathway in order to inhibit pain signals. The process begins when pain sensory neurons, called nociceptors, detect a potentially damaging stimulus. Spinal cord: Ascending and descending tracts | Kenhub Spinothalamic & spinoreticular tracts Tractus spinothalamicus & tractus spinoreticularis 1/8 As the overseer of the majority of the body's physiological processes, the brain has nu...